If you are thinking of using clear acrylic sheeting such as Perspex or Plexiglass in your bunny enclosure or to do some bunny proofing then here is some tips on how to do this safely as well as some ideas of how other bunny owners have put it to good use.
The advantages of using acrylic can give you a large solid barrier which can be used to contain the spread of mess but still allow you to see what your rabbits doing. Acrylic is also wipe clean and will avoid damage from toilet mess which would cause wood to warp or decay. It will also be a lot more resistant to chewing and scratching then wood which can be on the menu for a bored and hungry bunny.
One of the main drawbacks of using acrylic is that it is a brittle material and when put under stress will often shatter. This makes it a hard material to work with as it will often break when cut or if screwed down too tightly. This can also make it unsuitable if not used correctly in an enclosure, especially if it covers a large area, is fitted poorly and is not strong enough. It can be dangerous if it does smash for some reason as it will break into sharp shards which could easily cause harm. If you are thinking of using it always make sure its strong enough and fitted securely.
Another drawback Is it can quickly become scratched and damaged making it less appealing and if it's in an area where your rabbit spends time eating or is near where it goes to the toilet these scuffed areas would become hard to clean.
Another thing to consider is that although rabbits don't vocalize any noise they do enjoy smashing around and will quickly learn to use the surface to scratch and drum on which can become an annoyance.
Lastly be mindful that rabbits are a prey animal and often prefer a bit of cover when they relay. Always make sure they still have a shady area where they can feel less exposed to have a snooze in. If you create an environment with clear sides you may take away this scene of shelter.
One clever way this material can be put to use is when its mounted directly onto a wall to protect it. If for instance you have built a large pen that uses a wall as a part of its perimeter then fitting a sheet of clear material will stop any damage to the wallpaper or wall and be nicer looking, then if you were to cover it with another material such as wood. It can be flexible enough go all the way to the floor to cover over the base boards.